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货号: PH0338
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: MCM2
应用: IHC,WB,IF,ELISA
反应性 : Human,Mouse,
宿主物种 : Mouse
MW(CalcμLated) : 120kD
MW(Observed): 130kD
同种型-Isotype : IgG1,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein G
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-MCM2
抗原&靶点信息
特异性 : The antibody can specifically recognize human MCM2 protein. In western blotting of HEK293 cell lysate, the antibody can label a 130 kDa band.
基因名称 : MCM2 BM28 CCNL1 CDCL1 KIAA0030
蛋白名称 : DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
别名 : MCM2;BM28;CCNL1;CDCL1;KIAA0030;DNA replication licensing factor MCM2;Minichromosome maintenance protein 2 homolog;Nuclear protein BM28
背景:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012],


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