信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

p57kip2 (ABT-P57) mouse mAb

复制产品信息

说明书下载
货号: PH0332
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: p57
应用: IHC,WB,IF,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(CalcμLated) : 50kD
MW(Observed): 57kD
同种型-Isotype : IgG2a,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein G
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-P57

抗原&靶点信息

特异性 : This antibody detects endogenous levels of p57kip2 protein.
基因名称 : CDKN1C KIP2
蛋白名称 : Beckwith Wiedemann syndrome;BWCR;BWS;CDKI;CDKN 1C;CDKN1C;CDN1C_HUMAN;Cyclin dependent kinase inhibitor 1C;Cyclin dependent kinase inhibitor p57;Cyclin-dependent kinase inhibitor 1C;Cyclin-dependent kinase inhibitor p57;KIP 2;KIP2;p57;p57 Kip 2;p57KIP2;WBS
别名 : Beckwith Wiedemann syndrome;BWCR;BWS;CDKI;CDKN 1C;CDKN1C;CDN1C_HUMAN;Cyclin dependent kinase inhibitor 1C;Cyclin dependent kinase inhibitor p57;Cyclin-dependent kinase inhibitor 1C;Cyclin-dependent kinase inhibitor p57;KIP 2;KIP2;p57;p57 Kip 2;p57KIP2;WBS

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],

细胞定位 : Nuclear

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交