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货号: PH0594
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Vinculin
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Mouse
MW(CalcμLated) : 124kD
MW(Observed): 124kD
同种型-Isotype : IgG2a,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein G
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT2221
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Vinculin protein.
基因名称 : VCL
蛋白名称 : Vinculin
别名 : VCL;Vinculin;Metavinculin
背景:
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],


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