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PLEC Polyclonal Antibody

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说明书下载
货号: PG7646
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: PLEC
应用: IHC,IF
反应性 : Human,Rat,Mouse
宿主物种 : Rabbit
MW(Observed): 515kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:50-300;IF 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : PLEC Polyclonal Antibody detects endogenous levels of protein.
基因名称 : PLEC PLEC1
蛋白名称 : Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes (reviewed in PMID: 9701547, 11854008, and 17499243). Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans (PMID: 8633055, 8698233). Until 2010, this locus was named plectin 1 (symbol PLEC1 in human; Plec1 in mouse and rat) and the gene product had been referred to as "hemidesmosomal protein 1" or &qu

细胞定位 : Cytoplasm, cytoskeleton . Cell junction, hemidesmosome .

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