产品服务
信号通路
说明书下载
货号: PG5474
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: FGD1
应用: WB
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 105kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of FGD1 at Human/Mouse
基因名称 : FGD1 FGDY ZFYVE3
蛋白名称 : FGD1
别名 : FYVE, RhoGEF and PH domain-containing protein 1;Faciogenital dysplasia 1 protein;Rho/Rac guanine nucleotide exchange factor FGD1;Rho/Rac GEF;Zinc finger FYVE domain-containing protein 3;
背景:
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011],


微信客服