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Cleaved PARP1 Rabbit mAb

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说明书下载
货号: PL1520
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: PARP
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Rabbit
MW(CalcμLated) : 25kD
MW(Observed): 25kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1000;WB 1:500-5000;IF 1:200-1000;ELISA 1:5000-20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0046R

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Cleaved PARP1.
基因名称 : PARP1
蛋白名称 : Poly [ADP-ribose] polymerase 1
别名 : PARP1;ADPRT;PPOL;Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasmic, Nuclear

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