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PARP-1 Monoclonal Antibody

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说明书下载
货号: PH1506
货期: 一周
价格: 100μL/2200
+


靶点: PARP
应用: WB,Flow Cyt,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 113kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : PARP-1 Monoclonal Antibody detects endogenous levels of PARP-1 protein.
基因名称 : PARP1
蛋白名称 : Poly [ADP-ribose] polymerase 1
别名 : PARP1;ADPRT;PPOL;Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .

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