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货号: PH1504
货期: 一周
价格: 100μL/2200
所属分类:
靶点: Pax-6
应用: WB,Flow Cyt,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 47kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : Pax-6 Monoclonal Antibody detects endogenous levels of Pax-6 protein.
基因名称 : PAX6
蛋白名称 : Paired box protein Pax-6
别名 : PAX6;AN2;Paired box protein Pax-6;Aniridia type II protein;Oculorhombin
背景:
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015],


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