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详细信息
推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0581
抗原&靶点信息
特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD366/TIM-3 protein.
基因名称 : HAVCR2 TIM3 TIMD3
蛋白名称 : Inducible T-cell costimulator (Activation-inducible lymphocyte immunomediatory molecule) (CD antigen CD278)
别名 : ICOS;AILIM;Inducible T-cell costimulator;Activation-inducible lymphocyte immunomediatory molecule;CD278;CD278 nanobody;ICOS nanobody;
背景:
The protein encoded byThis gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases.This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]


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