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CRMP-2 (phospho Ser522) Polyclonal Antibody

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说明书下载
货号: PF1404
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: CRMP-2
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 62kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-CRMP-2 (S522) Polyclonal Antibody detects endogenous levels of CRMP-2 protein only when phosphorylated at S522.
基因名称 : DPYSL2
蛋白名称 : Dihydropyrimidinase-related protein 2
别名 : DPYSL2;CRMP2;ULIP2;Dihydropyrimidinase-related protein 2;DRP-2;Collapsin response mediator protein 2;CRMP-2;N2A3;Unc-33-like phosphoprotein 2;ULIP-2

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

细胞定位 : Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Membrane . Tightly but non-covalently associated with membranes.

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