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货号: PH1114
货期: 一周
价格: 100μL/2200
所属分类：
靶点: Toll-like Receptor 7
应用： WB
反应性 ： Transfected
宿主物种 ： Mouse
MW(CalcμLated) ： 121kD
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:1000
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 ： Monoclonal
抗原&靶点信息
特异性 ： This antibody detects endogenous levels of Toll-like Receptor and does not cross-react with related proteins.
基因名称 ： tlr7
别名 ： PRO285;TLR 7;Tlr7;TLR7_HUMAN;Toll like receptor 7;Toll-like receptor 7;UNQ248.
背景：
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008],
细胞定位 ： Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endosome . Lysosome . Cytoplasmic vesicle, phagosome . Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. .
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