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Raptor (Phospho Ser792) Rabbit mAb

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货号: PL0366
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: Raptor
应用: WB,IF,IP,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 149kD
MW(Observed): 150kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Raptor (Phospho Ser792) antibody detects endogenous levels of Human Mouse Rat Raptor (phospho-Ser792).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ASsYS
基因名称 : RPTOR KIAA1303 RAPTOR
蛋白名称 : Raptor (Ser792)
别名 : Regulatory-associated protein of mTOR;Raptor;p150 target of rapamycin;TOR;-scaffold protein;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

细胞定位 : Cytoplasm. Lysosome. Cytoplasmic granule . Targeting to lysosomes depends on amino acid availability. In arsenite-stressed cells, accumulates in stress granules when associated with SPAG5 and association with lysosomes is drastically decreased.

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