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详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : EHMT1 Monoclonal Antibody detects endogenous levels of EHMT1 protein.
基因名称 : EHMT1
蛋白名称 : Histone-lysine N-methyltransferase, H3 lysine-9 specific 5
别名 : EHMT1;EUHMTASE1;GLP;KIAA1876;KMT1D;Histone-lysine N-methyltransferase EHMT1;Euchromatic histone-lysine N-methyltransferase 1;Eu-HMTase1;G9a-like protein 1;GLP;GLP1;Histone H3-K9 methyltransferase 5;H3-K9-HMTase 5;Lysine N-methy
背景:
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],


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