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货号: PD0910
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: SESN3
应用: WB,ELISA,IHC
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 54kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of SESN3 at Human/Mouse
基因名称 : SESN3 SEST3
蛋白名称 : SESN3
背景:
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],


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