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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0176
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of IL-4 protein.
基因名称 ： IL4
蛋白名称 ： Receptor-type tyrosine-protein phosphatase C (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
别名 ： B220 antibody;CD 45 antibody;CD45 antibody;CD45 antigen antibody;CD45R antibody;GP180 antibody;L-CA antibody;LCA antibody;Leukocyte common antigen antibody;loc antibody;Ly-5 antibody;LY5 antibody;Ly5;homolog of antibody;Lyt-4 antibody;OTTHUMP00000033813 antibody;OTTHUMP00000033816 antibody;OTTHUMP00000033817 antibody;OTTHUMP00000038574 antibody;Protein tyrosine phosphatase receptor type c polypeptide antibody;Protein tyrosine phosphatase;receptor type C antibody;protein tyrosine phosphatase;receptor type;C antibody;Protein tyrosine phosphatase;receptor type;c polypeptide antibody;Ptprc antibody;PTPRC_HUMAN antibody;Receptor-type tyrosine-protein phosphatase C antibody;T200 antibody;T200 glycoprotein antibody;T200 leukocyte common antigen antibody;CD45 nanobody;
背景：
The protein encoded byThis gene is a pleiotropic cytokine produced by activated T cells.This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions ofThis cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal ofThis cytokine.This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, withThis gene particularly close to IL13.This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants ofThis gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
细胞定位 ： Secreted.
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