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详细信息
推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0175
抗原&靶点信息
特异性 : This recombinant monoclonal antibody can detects endogenous levels of IL-4 protein.
基因名称 : IL4
蛋白名称 : Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (gp67) (CD antigen CD33)
别名 : CD33;SIGLEC3;Myeloid cell surface antigen CD33;Sialic acid-binding Ig-like lectin 3;Siglec-3;gp67;CD antigen CD33;CD33 nanobody;
背景:
The protein encoded byThis gene is a pleiotropic cytokine produced by activated T cells.This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions ofThis cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal ofThis cytokine.This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, withThis gene particularly close to IL13.This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants ofThis gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]


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