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推荐稀释比 ： IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
组成 ： PBS, pH 7.4
纯化工艺 ： Protein A
储存 ： Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
克隆号 ： Monoclonal
抗原&靶点信息
特异性 ： Endogenous
基因名称 ： CD1C
蛋白名称 ： T-cell surface glycoprotein CD1c
别名 ： CD1C;T-cell surface glycoprotein CD1c;CD1c
背景：
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008],
细胞定位 ： Cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein. Lysosome . Subject to intracellular trafficking between the cell membrane and endosomes. .
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