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SOCS-1 Mouse mAb(5C3)

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说明书下载
货号: PH0774
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: SOCS-1
应用: IHC,WB
反应性 : Human,Mouse,Rat
宿主物种 : Mouse
MW(Observed): 23kD

隐藏域元素占位

详细信息

推荐稀释比 : IHC1:50-200;WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Monoclonal
克隆号 : 5C3

抗原&靶点信息

特异性 : This antibody detects endogenous levels of SOCS-1 at Human, Mouse,Rat
基因名称 : SOCS1 SSI1 TIP3
蛋白名称 : SOCS-1
别名 : Suppressor of cytokine signaling 1;SOCS-1;JAK-binding protein;JAB;STAT-induced STAT inhibitor 1;SSI-1;Tec-interacting protein 3;TIP-3;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Cytoplasmic vesicle . Detected in perinuclear cytoplasmic vesicles upon interaction with FGFR3.

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