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详细信息
推荐稀释比 ： WB 1:500-2000;IHC 1:50-300
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： MRP3 Polyclonal Antibody detects endogenous levels of MRP3 protein.
基因名称 ： ABCC3
蛋白名称 ： Canalicular multispecific organic anion transporter 2
别名 ： ABCC3;CMOAT2;MLP2;MRP3;Canalicular multispecific organic anion transporter 2;ATP-binding cassette sub-family C member 3;Multi-specific organic anion transporter D;MOAT-D;Multidrug resistance-associated protein 3
背景：
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],
细胞定位 ： Basolateral cell membrane ; Multi-pass membrane protein .
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