产品服务
信号通路
货号: PH1679
货期: 一周
价格: 100μL/2200
所属分类:
靶点: Fibrinogen β
应用: WB,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 56kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : Fibrinogen β Monoclonal Antibody detects endogenous levels of Fibrinogen β protein.
基因名称 : FGB
蛋白名称 : Fibrinogen beta chain
别名 : FGB;Fibrinogen beta chain
背景:
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014],


微信客服