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DYL1 rabbit pAb

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说明书下载
货号: PD1004
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: DYL1
应用: IHC,IF
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 10kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:50-200;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of DYL1 at Human/Mouse/Rat
基因名称 : DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1
蛋白名称 : DYL1

数据库链接:

Organism

基因 ID

SwissProt

背景:

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton . Nucleus . Mitochondrion . Upon induction of apoptosis translocates together with BCL2L11 to mitochondria. .

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