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GRK2 mouse mAb

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说明书下载
货号: PH1249
货期: 一周
价格: 100μL/2200
+


靶点: GRK 2
应用: WB
反应性 : Human
宿主物种 : Mouse
MW(Observed): 80kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of GRK2 and does not cross-react with related proteins.
基因名称 : adrbk1
别名 : ADRBK1;BARK;BARK1;GRK2;Beta-adrenergic receptor kinase 1;Beta-ARK-1;G-protein coupled receptor kinase 2

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Cell membrane . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .

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