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AP2M1 (Phospho Thr156) rabbit pAb

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货号: PF0662
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: AP2M1
应用: WB
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 47kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human AP2M1 (phospho-Thr156)
基因名称 : AP2M1 CLAPM1 KIAA0109
蛋白名称 : AP-2 complex subunit mu
别名 : AP-2 complex subunit mu;AP-2 mu chain;Adapter-related protein complex 2 mu subunit;Adaptin-mu2;Adaptor protein complex AP-2 subunit mu;Clathrin assembly protein complex 2 medium chain;Clathrin coat assembly protein AP50;Clathrin coat-associated protein AP50;HA2 50 kDa subunit;Plasma membrane adaptor AP-2 50 kDa protein;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015],

细胞定位 : Cell membrane . Membrane, coated pit ; Peripheral membrane protein; Cytoplasmic side. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV. .

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