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CaMK2 (Phospho Thr286) Antibody

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说明书下载
货号: PF0672
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;ELISA(peptide)1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous pospho levels of human CaMK2 (Phospho-Thr286)
基因名称 : CAMK2D CAMKD
蛋白名称 : CaMK2 (Phospho-Thr286)
别名 : Calcium/calmodulin-dependent protein kinase type II subunit delta;CaM kinase II subunit delta;CaMK-II subunit delta;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

细胞定位 : Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .

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