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CD72 (PN0545) Nb-FC recombinant antibody

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说明书下载
货号: PA0145
货期: 现货
价格: 100ug/2200
+


靶点: CD16
应用: ELISA,FC
反应性 : Human

隐藏域元素占位

详细信息

推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0531

抗原&靶点信息

特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD16 protein.
基因名称 : FCGR3A CD16A FCG3 FCGR3 IGFR3
蛋白名称 : B-cell differentiation antigen CD72 (Lyb-2) (CD antigen CD72)
别名 : CD72;B-cell differentiation antigen CD72;Lyb-2;CD72;CD72 nanobody;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses.This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded byThis gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations inThis gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq,

细胞定位 : Cell membrane ; Single-pass type I membrane protein . Secreted . Exists also as a soluble receptor. .

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