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货号: PH1481
货期: 一周
价格: 100μL/2200
靶点: PTH/PTHrP-R
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 66kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : PTH/PTHrP-R Monoclonal Antibody detects endogenous levels of PTH/PTHrP-R protein.
基因名称 : PTH1R
蛋白名称 : Parathyroid hormone/parathyroid hormone-related peptide receptor
别名 : PTH1R;PTHR;PTHR1;Parathyroid hormone/parathyroid hormone-related peptide receptor;PTH/PTHrP type I receptor;PTH/PTHr receptor;Parathyroid hormone 1 receptor;PTH1 receptor
背景:
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],


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