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TRPM2 rabbit pAb

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说明书下载
货号: PG5146
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: TRPM2
应用: WB
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 165kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of TRPM2 at Human/Mouse
基因名称 : TRPM2 EREG1 KNP3 LTRPC2 TRPC7
蛋白名称 : TRPM2

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016],

细胞定位 : Cell membrane ; Multi-pass membrane protein . Perikaryon . Cell projection . Cytoplasmic vesicle . Lysosome . Detected at the cell membrane and in intracellular vesicles in cortical neurons. Detected on neuronal cell bodies and neurites (By similarity). Detected on the cell membrane in polymorphonuclear neutrophils. Detected on cytoplasmic vesicles and lysosomes in immature bone marrow dendritic cells (By similarity). .; [Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Cell membrane ; Multi-pass membrane protein .; [Isoform 3]: Cell membrane ; Multi-pass membrane protein .

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