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CD35 Polyclonal Antibody

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说明书下载
货号: PD2314
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CD35
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 220kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:10000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CD35 Polyclonal Antibody detects endogenous levels of CD35
蛋白名称 : CD35
别名 : complement component;3b/4b;receptor 1/2;Knops blood group;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants

细胞定位 : Membrane ; Single-pass type I membrane protein.

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