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货号: PK0186
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Factor IX
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 16kD,45kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000-2000;ELISA 1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Human,Mouse,Rat FA9 (light chain, Cleaved-Arg191, protein was cleaved amino acid sequence between 191-200 )
基因名称 : F9 Factor IX
蛋白名称 : FA9 (light chain, Cleaved-Arg191)
别名 : Coagulation factor IX;Christmas factor;Plasma thromboplastin component;PTC;[Cleaved into: Coagulation factor IXa light chain;Coagulation factor IXa heavy chain]
背景:
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015],


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