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Claudin-4 (phospho Tyr208) Polyclonal Antibody

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说明书下载
货号: PF0832
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Claudin-4
应用: IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(CalcμLated) : 22kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-Claudin-4 (Y208) Polyclonal Antibody detects endogenous levels of Claudin-4 protein only when phosphorylated at Y208.
基因名称 : CLDN4
蛋白名称 : Claudin-4
别名 : CLDN4;CPER;CPETR1;WBSCR8;Claudin-4;Clostridium perfringens enterotoxin receptor;CPE-R;CPE-receptor;Williams-Beuren syndrome chromosomal region 8 protein

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013],

细胞定位 : Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .

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