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TLR8 Polyclonal Antibody

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说明书下载
货号: PG3339
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: TLR8
应用: IHC,IF
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-500;IF 1:50-200
组成 : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Polyclonal

抗原&靶点信息

特异性 : The antibody detects endogenous TLR8 protein.
基因名称 : TLR8
蛋白名称 : Toll-like receptor 8
别名 : Toll-like receptor 8;CD288

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008],

细胞定位 : Endosome membrane ; Single-pass type I membrane protein . Endosomal localization confers distinctive proteolytic processing. .

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