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Caspase-10 Polyclonal Antibody

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说明书下载
货号: PD2854
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Caspase-10
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 58kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Caspase-10 Polyclonal Antibody detects endogenous levels of Caspase-10 protein.
基因名称 : CASP10
蛋白名称 : Caspase10
别名 : CASP10;MCH4;Caspase-10;CASP-10;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],

细胞定位 : cytosol,CD95 death-inducing signaling complex,ripoptosome,

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