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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0544
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD45 protein.
基因名称 ： PTPRC CD45
蛋白名称 ： Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
别名 ： ACT 35 antibody;ACT35 antibody;ACT35 antigen antibody;ATC35 antigen antibody;CD 134 antibody;CD134 antibody;CD134 antigen antibody;IMD16 antibody;Lymphoid activation antigene ACT35 antibody;OX 40 antibody;OX40 antibody;OX40 antigen antibody;OX40 cell surface antigen antibody;OX40 homologue antibody;OX40L receptor antibody;TAX transcriptionally activated glycoprotein 1 receptor antibody;TAX transcriptionally-activated glycoprotein 1 receptor antibody;TNF receptor superfamily member 4 antibody;TNFRSF 4 antibody;TNFRSF4 antibody;TNR4_HUMAN antibody;Tumor necrosis factor receptor superfamily member 4 antibody;Txgp 1l antibody;Txgp1 antibody;Txgp1l antibody
背景：
The protein encoded byThis gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation.This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants ofThis gene, which enc
细胞定位 ： Cell membrane ; Single-pass type I membrane protein . Membrane raft . Colocalized with DPP4 in membrane rafts. .
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