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TIRAP Polyclonal Antibody

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说明书下载
货号: PD3251
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: TIRAP
应用: IHC,IF,WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 24kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : TIRAP Polyclonal Antibody detects endogenous levels of TIRAP protein.
基因名称 : TIRAP
蛋白名称 : Toll/interleukin-1 receptor domain-containing adapter protein
别名 : TIRAP;MAL;Toll/interleukin-1 receptor domain-containing adapter protein;TIR domain-containing adapter protein;Adaptor protein Wyatt;MyD88 adapter-like protein

数据库链接:

Organism

基因 ID

SwissProt

背景:

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Cell membrane . Membrane . Colocalizes with DAB2IP at the plasma membrane.

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