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Sp1 (Acetyl Lys703) rabbit pAb

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货号: PS0128
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Sp1
应用: WB,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 90kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Acetyl
推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human,Mouse,Rat Sp1 (Acetyl Lys703)
基因名称 : SP1 TSFP1
蛋白名称 : Sp1 (Acetyl Lys703)
别名 : Transcription factor Sp1

数据库链接:

Organism

基因 ID

SwissProt

背景:

function:Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.,PTM:O-glycosylated; contains N-acetylglucosamine side chains.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with ATF7IP, ATF7IP2, POGZ, HCFC1, AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.,

细胞定位 : Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.

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