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TGFBR2 (Phospho Tyr284) rabbit pAb

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说明书下载
货号: PF0284
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: TGF β Receptor II
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 62kD
MW(Observed): 75kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of TGFBR2 (Phospho-Tyr284) at Human, Mouse,Rat
基因名称 : TGFBR2
蛋白名称 : TGFBR2 (Phospho-Tyr284)
别名 : TGF-beta receptor type-2;TGFR-2;TGF-beta type II receptor;Transforming growth factor-beta receptor type II;TGF-beta receptor type II;TbetaR-II;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane ; Single-pass type I membrane protein . Membrane raft .; [Isoform 3]: Secreted .

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