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CD22 (PN0608) Nb-FC recombinant antibody

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说明书下载
货号: PA0249
货期: 现货
价格: 100ug/2200
+


靶点: CD142
应用: FC,ELISA
反应性 : Human

隐藏域元素占位

详细信息

推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0283

抗原&靶点信息

特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD142 protein.
基因名称 : F3
蛋白名称 : B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)
别名 : CD22;SIGLEC2;B-cell receptor CD22;B-lymphocyte cell adhesion molecule;BL-CAM;Sialic acid-binding Ig-like lectin 2;Siglec-2;T-cell surface antigen Leu-14;CD antigen CD22

数据库链接:

Organism

基因 ID

SwissProt

背景:

CD142, also known as Tissue Factor (TF), Coagulation Factor III, and Thromboplastin, is a 45 kD type I transmembrane glycoprotein. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells (cytoplasmic inclusions), astrocytes, myocardium, liver stromal cells, pancreas cells, and is also expressed on activated monocytes and stimulated endothelial cells. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis, atherosclerosis, and cancer.

细胞定位 : [Isoform 1]: Membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .

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