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EPAS-1 Polyclonal Antibody

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说明书下载
货号: PD2656
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: EPAS-1
应用: IF,WB,IHC,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 96kD
MW(Observed): 110-120kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IF 1:50-200;WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;Not yet tested in other applications;
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : EPAS-1 Polyclonal Antibody detects endogenous levels of EPAS-1 protein.
基因名称 : EPAS1 BHLHE73 HIF2A MOP2 PASD2
蛋白名称 : Endothelial PAS domain-containing protein 1
别名 : EPAS1;BHLHE73;HIF2A;MOP2;PASD2;Endothelial PAS domain-containing protein 1;EPAS-1;Basic-helix-loop-helix-PAS protein MOP2;Class E basic helix-loop-helix protein 73;bHLHe73;HIF-1-alpha-like factor;HLF;Hypoxia-inducible factor 2-alpha;HIF-2-alpha;HIF2-alpha;Member of PAS protein 2;PAS domain-containing protein 2

数据库链接:

Organism

基因 ID

SwissProt

背景:

endothelial PAS domain protein 1(EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009],

细胞定位 : Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. .

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