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推荐稀释比 ： Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:IHC 1:50-300;IF 1:200.
组成 ： Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
纯化工艺 ： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 ： Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
浓度 ： 1mg/ml
克隆性 ： Monoclonal
克隆号 ： 8F11
抗原&靶点信息
特异性 ： α-tubulin Monoclonal Antibody(8F11) AbFluor™ 405 Conjugated specially designed for your Immunofluorescence analysis.
基因名称 ： TUBA1A
蛋白名称 ： Tubulin alpha-1A chain
别名 ： TUBA1A
数据库链接：
背景：
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
细胞定位 ： Cytoplasm, cytoskeleton.
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