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货号: PH0975
货期: 两周
价格: 100μL/2200
所属分类:
靶点: TBP/TATA Binding Protein
应用: WB
反应性 : Human,Rat,Mouse
宿主物种 : Mouse
MW(CalcμLated) : 38kD
同种型-Isotype : IgG
偶联-Conjugate : HRP
隐藏域元素占位
详细信息
推荐稀释比 : Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:WB 1:1000-2000.
组成 : Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
浓度 : 1mg/ml
克隆性 : Monoclonal
克隆号 : 4H2
抗原&靶点信息
特异性 : TBP/TATA Binding Protein Monoclonal Antibody(4H2) HRP Conjugated, specially designed for your Western blot analysis.
基因名称 : TBP
蛋白名称 : TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
别名 : TBP;GTF2D1;TF2D;TFIID;TATA-box-binding protein;TATA sequence-binding protein;TATA-binding factor;TATA-box factor;Transcription initiation factor TFIID TBP subunit
背景:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin


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