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HNF1α (Phospho Ser247) rabbit pAb

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货号: PF0576
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: HNF1A
应用: WB
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 69kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human HNF1α (phospho-Ser247)
基因名称 : HNF1A TCF1
蛋白名称 : HNF1α (Ser247)
别名 : Hepatocyte nuclear factor 1-alpha;HNF-1-alpha;HNF-1A;Liver-specific transcription factor LF-B1;LFB1;Transcription factor 1;TCF-1;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

细胞定位 : Nucleus .

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