信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

p27Kip1 (ABT-p27) mouse mAb

复制产品信息

说明书下载
货号: PH0323
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: p27
应用: IHC,WB,IF,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(CalcμLated) : 22kD
MW(Observed): 24kD
同种型-Isotype : IgG1,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein G
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-p27

抗原&靶点信息

特异性 : This antibody detects endogenous levels of p27Kip1 protein.
基因名称 : CDKN1B KIP1
蛋白名称 : Cyclin-dependent kinase inhibitor 1B
别名 : CDKN1B;KIP1;Cyclin-dependent kinase inhibitor 1B;Cyclin-dependent kinase inhibitor p27;p27Kip1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014],

细胞定位 : Nuclear

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交