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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0025
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD44 protein.
基因名称 ： CD44 LHR MDU2 MDU3 MIC4
蛋白名称 ： Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)
别名 ： MRC1;CLEC13D;CLEC13DL;MRC1L1;Macrophage mannose receptor 1;MMR;C-type lectin domain family 13 member D;C-type lectin domain family 13 member D-like;Macrophage mannose receptor 1-like protein 1;CD206
背景：
The protein encoded byThis gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs).This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts forThis gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity ofThis protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
细胞定位 ： Cell membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli. Localizes to cholesterol-rich membrane-bound lipid raft domains. .
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