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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0420
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD86 protein.
基因名称 ： CD86 CD28LG2
蛋白名称 ： Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form]
别名 ： Blast 2 antibody;BLAST-2 antibody;Blast2 antibody;C type lectin domain family 4 member J antibody;C-type lectin domain family 4 antibody;C-type lectin domain family 4 member J antibody;C-type lectin domain family 4;member J antibody;CD 23 antibody;CD 23A antibody;CD23 antibody;CD23 antigen antibody;CD23A antibody;CLEC 4J antibody;CLEC4J antibody;Fc epsilon receptor II antibody;Fc epsilon RII antibody;Fc fragment of IgE antibody;Fc fragment of IgE low affinity II receptor for antibody;Fc fragment of IgE receptor II antibody;Fc fragment of IgE;low affinity II;receptor for;CD23;antibody;Fc of IgE antibody;Fc of IgE;low affinity II;receptor for;CD23;antibody;Fc receptor IgE low affinity II alpha polypeptide antibody;Fc receptor;IgE;low affinity II;alpha polypeptide;isoform CRA_a antibody;Fc-epsilon-RII antibody;FCE 2 antibody;FCE2 antibody;FCER 2 antibody;Fcer2 antibody;FCER2_HUMAN antibody;FCER2A antibody;FceRII antibody;IgE binding factor antibody;IgE receptor lymphocyte antibody;IgE-binding factor antibody;IGEBF antibody;Immunoglobulin E binding factor antibody;Immunoglobulin E receptor antibody;Immunoglobulin E receptor;low affinity II antibody;Immunoglobulin E-binding factor antibody;Immunoglobulin epsilon chain antibody;LEUKOCYTE ANTIGEN CD23 antibody;Low Affinity IgE Receptor antibody;Low affinity immunoglobulin epsilon Fc receptor antibody;Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody;Low affinity immunoglobulin epsilon Fc receptor soluble form antibody;Ly-42 antibody;Ly42 antibody;Lymphocyte antigen CD23 antibody;Lymphocyte IgE receptor antibody;MGC93219 antibody;CD23 nanobody;
背景：
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily.This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding ofThis protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding ofThis protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
细胞定位 ： Cell membrane; Single-pass type I membrane protein.
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