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MEK-6 (phospho Ser207) Polyclonal Antibody

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说明书下载
货号: PF1743
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-MEK-6 (S207) Polyclonal Antibody detects endogenous levels of MEK-6 protein only when phosphorylated at S207.
基因名称 : MAP2K6
蛋白名称 : Dual specificity mitogen-activated protein kinase kinase 6
别名 : MAP2K6;MEK6;MKK6;PRKMK6;SKK3;Dual specificity mitogen-activated protein kinase kinase 6;MAP kinase kinase 6;MAPKK 6;MAPK/ERK kinase 6;MEK 6;Stress-activated protein kinase kinase 3;SAPK kinase 3;SAPKK-3;SAPKK3

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Binds to microtubules.

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