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JNK2 Rabbit Polyclonal Antibody

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货号: PG3290
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: JNK2
应用: WB,IHC,IF
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 46,54kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : The antibody detects endogenous JNK2 protein
基因名称 : MAPK9 JNK2 PRKM9 SAPK1A
蛋白名称 : Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)
别名 : Mitogen-activated protein kinase 9;MAP kinase 9;MAPK 9;JNK-55;Stress-activated protein kinase 1a;SAPK1a;Stress-activated protein kinase JNK2;c-Jun N-terminal kinase 2;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternative

细胞定位 : Cytoplasm . Nucleus . Colocalizes with POU5F1 in the nucleus. .

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