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C/EBP β (Acetyl Lys265) rabbit pAb

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货号: PS0194
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: C/EBP β
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 40kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Acetyl
推荐稀释比 : WB 1:1000-2000;ELISA 1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human,Mouse,Rat C/EBP β (Acetyl Lys265)
基因名称 : CEBPB LAP TCF5 PP9092
蛋白名称 : C/EBP β (Acetyl Lys265)
别名 : CCAAT/enhancer-binding protein beta;C/EBP beta;Liver activator protein;Nuclear factor NF-IL6;Transcription factor 5;TCF-5;

数据库链接:

Organism

基因 ID

SwissProt

背景:

function:Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'.,PTM:Sumoylated by polymeric chains of SUMO2 or SUMO3.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha, delta and gamma. Interacts with TRIM28 and PTGES2.,tissue specificity:Expressed at low levels in the lung, kidney and spleen.,

细胞定位 : Nucleus . Cytoplasm . Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity). .

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