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货号: PH0536
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: p300
应用: WB,IF,ELISA
反应性 : Human,Mouse,
宿主物种 : Mouse
MW(CalcμLated) : 264kD
MW(Observed): 264kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein G
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PTR2539
抗原&靶点信息
特异性 : This antibody detects endogenous levels of p300 protein.
基因名称 : EP300
蛋白名称 : Histone acetyltransferase p300
别名 : EP300;P300;Histone acetyltransferase p300;p300 HAT;E1A-associated protein p300
背景:
E1A binding protein p300(EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008],


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