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货号: PH0608
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: CKR-5
应用: Flow Cyt,ELISA
反应性 : Human
宿主物种 : Mouse
MW(Observed): 40kD
同种型-Isotype : IgG1,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成 : Phosphate-buffered solution
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PTR1380
抗原&靶点信息
特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD195 protein.
基因名称 : CCR5 CMKBR5
蛋白名称 : C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)
别名 : C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD antigen CD195;
背景:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok


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