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详细信息
推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0595
抗原&靶点信息
特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD11b protein.
基因名称 : ITGAM CD11B CR3A
蛋白名称 : Endoglin (CD antigen CD105)
别名 : Endoglin;CD antigen CD105;
背景:
integrin subunit alpha M(ITGAM) Homo sapiens This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Mar 2009]


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